Low-Dose Naltrexone in Perimenopause: What You Should Know
LDN is gaining traction as a complementary therapy during perimenopause. Here's how it works, what the evidence shows, and how it might fit alongside your hormone optimization plan.
You may have seen the letters “LDN” popping up in your feed or heard a friend mention . It stands for Low-dose naltrexone, and it’s one of the most talked-about additions to perimenopause care right now, and for good reason.
It’s not a hormone. It works on a completely different layer of your health, helping to calm the quiet, low-grade inflammation that tends to ramp up during hormonal transitions.
The kind that leaves you with lingering joint pain, fragile sleep, stubborn brain fog, or a constant preoccupation with food that has nothing to do with hunger.
In our latest article, we walk through:
→ What LDN actually is and how it works
→ Why it’s showing up specifically in perimenopause care
→ The symptoms it may help with, including one most women don’t expect
→ How it fits alongside hormone therapy without replacing any part of it
→ What starting it actually looks like
If you’ve been optimizing and still feel like something is unresolved, this might be the missing layer worth exploring.